When looking to play 5 reel slots real money, it’s important to choose a reputable online casino that offers a wide selection of games. Make sure to check the security and licensing of the casino before depositing any funds. Keep in mind that 5 reel slots provide more paylines and opportunities to win compared to traditional 3 reel slots. Set a budget and stick to it to ensure responsible gaming practices. Take advantage of bonuses and promotions to increase your chances of winning while playing 5 reel slots for real money.