When searching for the best payout online slots, it is essential to consider the return to player (RTP) percentage, as higher RTP slots offer better chances of winning. Additionally, look for slots with bonus features like free spins or multipliers, as these can enhance your winnings. Reading reviews and player feedback can also help in finding slots with favorable payout rates. Keep in mind that progressive jackpot slots usually have lower RTP but offer the chance to win big. Finally, establish a budget and stick to it to ensure a positive gaming experience.