When selecting winning Powerball numbers, consider using a mix of both high and low numbers to improve your odds. Additionally, including both even and odd numbers can also help diversify your ticket. Many experts suggest avoiding common number combinations, such as birthdays, to reduce the chance of sharing the jackpot. Utilizing a random number generator can help eliminate any biases in your number selection process. Finally, remember that the odds of winning the Powerball jackpot are very low, so play responsibly and within your means.