When researching what online casino has the best payouts, it is crucial to consider factors such as the payout percentage, game selection, and user reviews. Look for casinos that offer high payout percentages to increase your chances of winning. Additionally, check if the casino has a good reputation for paying out winnings promptly. Reading player feedback can provide valuable insights into the actual payout experience at a particular online casino. Conduct thorough research to find a reputable online casino that consistently offers the best payouts.